Chronic fatigue and ME
- enquiries4982
- Oct 22
- 2 min read
🌿 Struggling with chronic fatigue? You’re not alone.Long-term exhaustion that rest doesn’t fix can feel overwhelming — yet it often remains misunderstood here’s a breakdown of what we’re seeing with Chronic Fatigue Syndrome (CFS) / Myalgic Encephalomyelitis (ME) — the terms are often used interchangeably, though sometimes ME refers to CFS plus inflammation.
✅ What it is
Persistent physical and cognitive fatigue, often not relieved by sleep or rest.
Other symptoms can include:
Post-exertional malaise (feeling far worse after even minor exertion)
Muscle and joint pain
Unrefreshing sleep
Flu-like symptoms: sore throat, tender lymph nodes
Mood disturbances
⚠️ How it affects the body
This isn’t just “being tired” — it’s a multi-system challenge. Some of the key factors involved include:
Infections: viruses like Epstein–Barr virus (EBV) often show up in people with symptoms consistent with CFS/ME.
Immune system dysregulation: changes in cytokines, NK cells, CD8 suppressor cells — suggesting a chronic, low-level immune activation.
Hormonal / HPA axis issues: for example low cortisol levels (hypocortisolism) have been observed.
Mitochondrial dysfunction & oxidative stress: reduced antioxidant enzyme activity (like SOD, GPx), sleep dysregulation, melatonin issues.
Gut-brain axis and serotonin: alterations in serotonin transporter activity have been noted, along with gut dysbiosis and GI symptoms being common.
💡 Why it matters to take action
Because CFS/ME — when left unaddressed — can become deeply disruptive: work, family life, social life, even day-to-day tasks can get harder and harder. But you don’t have to just “live with it”. With the right support focused on root causes (rather than just “manage the symptoms”), meaningful improvements are possible.
📞 Meet Rachael at The Better Living Clinic
Here’s where help comes in:At The Better Living Clinic, Rachael Knight specialises in chronic fatigue, working on a holistic, personalised basis to explore and support:
the underlying infections or immune issues
mitochondrial & oxidative stress support
gut-brain axis and nutritional/wellness foundations
hormone/bio-stress systems
.

🗓 Book your consultation now
👉 If you’re ready to take the next step and explore how to regain your energy and vitality, book a consultation with Rachael today.Visit: www.thebetterlivingclinic.com to find out more about the clinic & schedule your session. You deserve to feel better, stronger and more in control






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